Anticardiolipin syndrome: antiphospholipid syndrome.

نویسنده

  • A E Gharavi
چکیده

North Am 2000;26:215–27. 14 Savill J. Recognition and phagocytosis of cells undergoing apoptosis. Br Med Bull 1997;53:491–508. 15 Elkon KB. Apoptosis in SLE – too little or too much? Review. Clin Exp Rheumatol 1994;12:553–9. 16 Drappa J, Vaishnaw AK, Sullivan KE, Chu JL, Elkon KB. Fas gene-mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. N Engl J Med 1996; 335:1643–9. 17 Vaishnaw AK, Sullivan KE, Elkon KB. The Canale-Smith syndrome. Reply. N Engl J Med 1997;336:1457–8. 18 Rovere P, Sabbadini MG, Fazzini F, Bondanza A, et al. Remnants of suicidal cells fostering systemic autoaggression. Apoptosis in the origin and maintenance of autoimmunity. Arthritis Rheum 2000;43: 1663–72. 19 Botto M, Dell’Agnola C, Bygrave AE, Thompson EM, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998;19:56–9. 20 Voll RE, Roth E, Herrmann M, Fehr H, et al. Histone-specific Th clones derived from systemic lupus-erythematosus patients display a Th0-like or Th1-like cytokine secretion pattern. Arthritis Rheum 1996;39: 1326. 21 Walport MJ, Davies KA, Botto M. C1q and systemic lupus erythematosus. Review. Immunobiology 1998;199:265–85. 22 Korb LC, Ahearn JM. C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. J Immunol 1997;158:4525–8. 23 Pickering MC, Walport MJ. Links between complement abnormalities and systemic lupus erythematosus. Rheumatology (Oxford) 2000;39:133–41. 24 Taylor PR, Carugati A, Fadok VA, Cook HT, et al. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med 2000;192:359–66.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Anticardiolipin Antibodies in Juvenile Rheumatoid Arthritis and Systemic Lupus Erythematosus

Background: Antiphospholipid antibody syndrome (APS) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in blood, measured by a standardized ELISA is the most acceptable laboratory criteria. APS IgG isotype, particularly IgG2 subclass is more strongly associated ...

متن کامل

Study of antiphospholipid antibodies in a patient with Sneddon's syndrome and her family.

BACKGROUND Sneddon's syndrome is a disease characterized by livedo reticularis and cerebrovascular lesions, with a hereditary transmission and unknown etiopathogenesis. A number of reports have documented a link between antiphospholipid antibodies and Sneddon's syndrome with different results. The present work was designed to sequentially study antiphospholipid antibodies in a patient with Sned...

متن کامل

Lupus anticoagulants and anticardiolipin antibodies: personal reminiscences, a little history, and some random thoughts.

See also Scully M-F. Moderate dose oral anticoagulant therapy in patients with the antiphospholipid syndrome? Yes. This issue, pp 840–1; Rickles FR, Marder VJ. Moderate dose oral anticoagulant therapy in patients with the antiphospholipid syndrome? No. This issue, pp 842–3; Khamashta MA, Hunt BJ. Moderate dose oral anticoagulant therapy in patients with the antiphospholipid syndrome? No. This i...

متن کامل

Lupus anticoagulant and anticardiolipin antibodies in SLE with secondary Antiphospholipid Antibody Syndrome.

Thirty patients with systemic lupus erythematosus (SLE) and suspected secondary antiphospholipid antibody syndrome (APLAS) were evaluated in the study based on their clinical manifestations. The aim was to study the prevalence of various antiphospholipid antibodies, compare the tests used for their detection and to find a correlation between clinical and laboratory parameters. Coagulation tests...

متن کامل

Audiovestibular manifestations of the antiphospholipid syndrome.

We report on two patients who have high titres of antiphospholipid antibodies, both of whom had acute audiovestibular failure. One of the patients had systemic lupus erythematosus. The other patient had primary antiphospholipid syndrome: audiovestibular symptoms have not been reported in this condition. The occurrence of acute audiovestibular failure in the primary antiphospholipid syndrome rai...

متن کامل

[The antiphospholipid syndrome].

The antiphospholipid syndrome (APS) defines the clinical association between antiphospholipid antibodies and a syndrome of hypercoagulability or thrombophilia (the term of "sticky blood" is sometimes used in APS). Antiphospholipid antibodies comprise a broad family of antibodies including both lupus anticoagulants and anticardiolipin antibodies. The pathogenesis of APS remains unclear. Neverthe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Clinical medicine

دوره 1 1  شماره 

صفحات  -

تاریخ انتشار 2001